MacOS profile not working in Ventura 13.1

Hello,

I've configured my home router to distribute by default the NextDNS IPv4 DNS servers through DHCP. 

Then I've generated and installed a MacOS profile for my MacMini M1 running Ventura 13.1.

No matter whether the profile is correctly installed, the OS is still using the NextDNS IPv4 servers.

sudo /usr/bin/profiles -P
Marco [1] attribute: profileIdentifier: io.nextdns.xxxxx.profile
There are 1 configuration profiles installed

scutil --dns
DNS configuration

resolver #1
  search domain[0] : router
  nameserver[0] : 45.90.28.32
  if_index : 13 (en1)
  flags    : Request A records
  reach    : 0x00000002 (Reachable)

resolver #2
  domain   : local
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300000

resolver #3
  domain   : 254.169.in-addr.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300200

resolver #4
  domain   : 8.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300400

resolver #5
  domain   : 9.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300600

resolver #6
  domain   : a.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300800

resolver #7
  domain   : b.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 301000

DNS configuration (for scoped queries)

resolver #1
  search domain[0] : router
  nameserver[0] : 45.90.28.32
  if_index : 13 (en1)
  flags    : Scoped, Request A records
  reach    : 0x00000002 (Reachable)

Connecting to test.nextdns.io using Safari

{
"status": "ok",
"protocol": "UDP",
"profile": "xxxxxxxxxxxxx",
"client": "xxxxxxxxxxxxx",
"srcIP": "xxxxxxxxxxxxx",
"destIP": "45.90.28.32",
"anycast": true,
"server": "zepto-mil-1",
"clientName": "unknown"
}

Connecting to test.nextdns.io using Microsoft Edge with manually configured NextDNS DoH 

{
"status": "ok",
"protocol": "DOH",
"profile": "xxxxxxxxxxxxx",
"client": "xxxxxxxxxxxxx",
"srcIP": "xxxxxxxxxxxxx",
"destIP": "192.145.127.148",
"anycast": false,
"server": "zepto-mil-1",
"clientName": "chrome",
"deviceName": "Edge MacOS",
"deviceID": "xxxxxxxxxxxxx"
}

What's wrong? How can I set up MacOS to use NextDNS DoH across all the OS?