UniFi CyberSecure by Proofpoint Compatibility?

I use the NextDNS CLI with my Unifi UDM SE and it works flawlessly.

I was debating about subscribing to the Unifi CyberSecure by Proofpoint offering but unsure if it will be compatible with the NextDNS CLI.  I don't think it uses DNS, but I can't verify.

Has anyone tried this?  I have the built-in Unifi IDS/IPS enabled with several threat categories in-use, and that hasn't caused any issues with NextDNS, so I'm assuming it piggy-backs off of that.