NextDNS protect DNS Spoofing?

Two questions:

I configure two stamps on the dnscrypt[.]info website, with the information of my NextDNS profile (IPv4 IPs, ID), copy and configure this in the DnsCloack APP, configure DoH, TCP in reverse UDP, do not use local cache in this APP, with anycast connection, will I be protected against "DNS Cache Poisoning"?

I configure my iOS 18 only with a valid Apple profile on my.nextdns.io, this protects my communication against "DNS Cache Poisoning"?