Setting up NextDNS on AWS EC2

Hello - we are currently trying to setup a proxy server on EC2 (AWS) so that we can resolve Handshake domains. When I try the

systemd-resolved

option, we are getting the following for all 4 DNS entries.

Failed to add DNS server address '2a07:a8c1::#<configid>.dns2.nextdns.io', ignoring: Invalid argument

Furthermore, we are also getting

/etc/systemd/resolved.conf:20: Unknown lvalue 'DNSOverTLS' in section 'Resolve'

Any help with this would be appreciated. Note that we got the configid on a browser using a local machine but set it up on the EC2 instance, and we didn't "link ip" so wondering if those have anything to do with it.