NextDNS profile not working on MacMini running Ventura 13.1

Hello,

I've configured my home router to distribute by default the NextDNS IPv4 DNS servers through DHCP. 

Then I've generated and installed a MacOS profile for my MacMini M1 running Ventura 13.1.

No matter whether the profile is correctly installed, the OS is still using the NextDNS IPv4 servers.

sudo /usr/bin/profiles -P
Marco [1] attribute: profileIdentifier: io.nextdns.xxxxx.profile
There are 1 configuration profiles installed

scutil --dns
DNS configuration

resolver #1
  search domain[0] : router
  nameserver[0] : 45.90.28.32
  if_index : 13 (en1)
  flags    : Request A records
  reach    : 0x00000002 (Reachable)

resolver #2
  domain   : local
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300000

resolver #3
  domain   : 254.169.in-addr.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300200

resolver #4
  domain   : 8.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300400

resolver #5
  domain   : 9.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300600

resolver #6
  domain   : a.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 300800

resolver #7
  domain   : b.e.f.ip6.arpa
  options  : mdns
  timeout  : 5
  flags    : Request A records
  reach    : 0x00000000 (Not Reachable)
  order    : 301000

DNS configuration (for scoped queries)

resolver #1
  search domain[0] : router
  nameserver[0] : 45.90.28.32
  if_index : 13 (en1)
  flags    : Scoped, Request A records
  reach    : 0x00000002 (Reachable)

Connecting to test.nextdns.io using Safari

{
"status": "ok",
"protocol": "UDP",
"profile": "xxxxxxxxxxxxx",
"client": "xxxxxxxxxxxxx",
"srcIP": "xxxxxxxxxxxxx",
"destIP": "45.90.28.32",
"anycast": true,
"server": "zepto-mil-1",
"clientName": "unknown"
}

Connecting to test.nextdns.io using Microsoft Edge with manually configured NextDNS DoH 

{
"status": "ok",
"protocol": "DOH",
"profile": "xxxxxxxxxxxxx",
"client": "xxxxxxxxxxxxx",
"srcIP": "xxxxxxxxxxxxx",
"destIP": "192.145.127.148",
"anycast": false,
"server": "zepto-mil-1",
"clientName": "chrome",
"deviceName": "Edge MacOS",
"deviceID": "xxxxxxxxxxxxx"
}

What's wrong? How can I set up MacOS to use NextDNS DoH across all the OS?